Study of relationship between metallothionein and heavy metals by chronopotentiometry stripping analysis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F04%3A00011227" target="_blank" >RIV/00216224:14310/04:00011227 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Study of relationship between metallothionein and heavy metals by chronopotentiometry stripping analysis

Original language description

The metallothionein (MT) is low molecular weight, intracellular and cysteine-rich proteins presenting high affinity for metal ions. Although the members of this family were discovered nearly 40 years ago, their functional significance remains obscure. MTs are involved in many pathophysiological processes such as metal ion homeostasis and detoxification, protection against oxidative damage, cell proliferation and apoptosis, chemoresistance and radiotherapy resistance. MT isoforms have been shown to be involved in several aspects of the carcinogenic process, cancer development and progression. MT expression has been implicated as a transient response to any form of stress or injury providing cytoprotective action. Although MT participates in the carcinogenic process and is used as a potential marker of tumor differentiation or cell proliferation, or as a predictor of poor prognosis remains unclear. Electrochemical measurements were performed with AUTOLAB Analyser (EcoChemie, Netherlands)

Czech name

Studium vztahu mezi metalothioneinem a tkými kovy pomocí chronopotenciometrické stripping analýzy

Czech description

Studium vztahu mezi metalothioneinem a tkými kovy pomocí chronopotenciometrické stripping analýzy

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CG - Electrochemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2004

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical Chemistry

ISSN

0009-9147

e-ISSN

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Volume of the periodical

50

Issue of the periodical within the volume

6

Country of publishing house

ES - SPAIN

Number of pages

2

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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