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Elimination voltammetry of oligonucleotides

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F04%3A00011234" target="_blank" >RIV/00216224:14310/04:00011234 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Elimination voltammetry of oligonucleotides

  • Original language description

    Oligodeoxynucleotides (ODNs) containing adenines (A), cytosines (C) and guanines (G) are electroactive species and produce cathodic (A,C) and anodic (G) voltammetric peaks at mercury electrodes. The reduction peak potentials of A and C are located very close to each other, so that usually only one voltammetric peak is observed. One signal only can be observed even when adsorptive transfer stripping voltammetry (AdTSV) is used. The elimination voltammetry with linear scan (EVLS) used in connection with ahanging mercury electrode is able to distinguish between A and C signals. The EVLS is based on elimination of one or two selected currents from total currents measured by linear scan voltammetry. The function eliminating kinetic and charging currents, and conserving the diffusion current was calculated for the case of adsorbed electroactive substance, and the theoretical elimination curve has a peak-counterpeak form. Various elimination functions were applied in the analysis of oligonuc

  • Czech name

    Eliminační voltametrie oligonukleotidů

  • Czech description

    Oligonukleotidy(ODNs) obsahující adenin (A), cytosin (C) a guanin (G) jsou elektroaktivní částice a produkují na rtuťové elektrodě katodické (A,C) a anodické (G) signály. Redukční píky A a C jsou potenciálově lokalizovány tak blízko, že splývají a běžnými elektrochemickými metodami jsme schopni registrovat signál jen jeden. Pomocí eliminační voltametrie s lineární polarizací elektrody(EVLS) se nám podařilo redukční píky A a C nejen rozlišit, ale i dokázat, že v kombinaci EVLS s adsorptvním strippingem lze uvažovat o rozlišení sekvence bází v jednotlivých ODNs.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CG - Electrochemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Book of Abstracts I - 55th Annual Meeting of the ISE

  • ISBN

  • ISSN

  • e-ISSN

  • Number of pages

    1

  • Pages from-to

    429-429

  • Publisher name

    International Society of Electrochemistry

  • Place of publication

    Thessaloniki, Creece

  • Event location

    Thessaloniki, Greece

  • Event date

    Sep 19, 2004

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article