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A sensor for investigating the interaction between biologically important heavy metals and glutathione

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F07%3A00020268" target="_blank" >RIV/00216224:14310/07:00020268 - isvavai.cz</a>

  • Alternative codes found

    RIV/62156489:43210/07:00107862 RIV/62157124:16270/07:00001309

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    A sensor for investigating the interaction between biologically important heavy metals and glutathione

  • Original language description

    Glutathione (GSH) is the water-soluble tripeptide playing a crucial role in number of cellular reactions including detoxification of heavy metals. Glutathione can be found both in oxidized (GSSG) and reduced (GSH) state. The aim of this work was to utilize the electrochemical methods for determining of glutathiones and for investigating interaction of GSH and cadmium, zinc, copper and nickel ions or food supplement for animal nutrition. It clearly follows from the results obtained that GSH and GSSG canbe distinguished by cyclic voltammetry whereas the height of their current response is proportional to their concentration. Moreover, we were concerned with studying of these interactions by cyclic voltammetry. The markedly changes of GSH signal were observed and discussed. The highest decrease of GSH reductive signal cause cadmium ions followed by zinc, nickel and copper ones. Moreover we observed that reductive GSH signal gradually decreased (about 9 %) with increasing concentration of

  • Czech name

    Senzor pro sledování interakcí mezi biologicky významnými těžkými kovy a glutathioneinem

  • Czech description

    Senzor pro sledování interakcí mezi biologicky významnými těžkými kovy a glutathioneinem

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CG - Electrochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GP525%2F04%2FP132" target="_blank" >GP525/04/P132: Study of protection mechanisms for stress-induced by heavy metals</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Czech J. Anim. Sci.

  • ISSN

    1212-1819

  • e-ISSN

  • Volume of the periodical

    52

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    6

  • Pages from-to

    37-43

  • UT code for WoS article

  • EID of the result in the Scopus database