Temporal vs. spatial variations in concentrations of compounds with specific modes of action in river sediment samples

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F07%3A00020383" target="_blank" >RIV/00216224:14310/07:00020383 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Temporal vs. spatial variations in concentrations of compounds with specific modes of action in river sediment samples
Original language description
In numerous studies the contamination of river sediments has been assessed both by chemical analysis and especially by bioassays from single time sampling reflecting just the actual situation. Two year study has been conducted to reveal the spatial and temporal-seasonal variability in the concentrations of commonly studied contaminants, but namely of the chemicals with specific modes of action in river sediments. Along with analysis of known pollutants we have assessed the overall potencies of the sediment extracts for cytotoxicity, dioxin-like, (anti)estrogenic and (anti)androgenic potency. Battery of in vitro bioassays with recombinant yeast and human cell systems was used to evaluate the extracts of sediments from four consequent sampling representing two different seasons. These bioassays show an integrative measure and identify the sites with continuously increased potencies for specific toxicity.
Czech name
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Czech description
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Project
<a href="/en/project/GP525%2F05%2FP160" target="_blank" >GP525/05/P160: In vitro models for study of endocrine disruption - effects of traditional and new types of persistent organic pollutants</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2007
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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