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Evaluation of genotoxic and non-genotoxic effects of organic air pollution using in vitro bioassays

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F07%3A00023700" target="_blank" >RIV/00216224:14310/07:00023700 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Evaluation of genotoxic and non-genotoxic effects of organic air pollution using in vitro bioassays

  • Original language description

    In this study, organic extracts of total suspended particles (TSP) and the particulate matter (PM) with the size below 2.5 um (PM2.5) combined with organic extracts of the gas phase (GP) collected at two urban and two background localities were analyzedwith a bacterial genotoxicity test, SOS chromotest, and an in vitro test for the dioxin toxicity determination, using a modified cell-line of rat hepatoma H4IIE.luc. In addition, the samples of TSP and GP were analyzed for PAHs contents. The PAHs concentrations and both of the toxic activities at the urban localities were much higher than ones at the background localities. Predominantly, traffic was a source of the urban air pollution there which was also confirmed by the evaluation of portions of certain PAHs (BaP/BPE, PYR/BaP) at the localities. On the other hand, the background localities were apparently affected by a long-distance transport of the pollutants from urban and industrial centers. The results of the bioassays indicated p

  • Czech name

    Hodnocení genotoxických a negenotoxických efektů organických polutantů volného ovzduší s využitím in vitro testů

  • Czech description

    In this study, organic extracts of total suspended particles (TSP) and the particulate matter (PM) with the size below 2.5 um (PM2.5) combined with organic extracts of the gas phase (GP) collected at two urban and two background localities were analyzedwith a bacterial genotoxicity test, SOS chromotest, and an in vitro test for the dioxin toxicity determination, using a modified cell-line of rat hepatoma H4IIE.luc. In addition, the samples of TSP and GP were analyzed for PAHs contents. The PAHs concentrations and both of the toxic activities at the urban localities were much higher than ones at the background localities. Predominantly, traffic was a source of the urban air pollution there which was also confirmed by the evaluation of portions of certain PAHs (BaP/BPE, PYR/BaP) at the localities. On the other hand, the background localities were apparently affected by a long-distance transport of the pollutants from urban and industrial centers. The results of the bioassays indicated p

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    DI - Pollution and air control

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Environment International

  • ISSN

    0160-4120

  • e-ISSN

  • Volume of the periodical

    33/7/2007

  • Issue of the periodical within the volume

    33/7/2007

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

    859-866

  • UT code for WoS article

  • EID of the result in the Scopus database