Genotoxic and non-genotoxic effects of organic air pollution

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F64608531%3A_____%2F03%3AT07" target="_blank" >RIV/64608531:_____/03:T07 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Genotoxic and non-genotoxic effects of organic air pollution
Original language description
Air pollution has generally been recognized as a health hazard. Adverse health effects are mainly related to persistent organic pollutants. In air, they are either bound to the particulate matter or in a volatile form. Besides PAHs, there are also theirderivatives. A large amount of these derivatives comes from transformation reactions of PAHs in air. This study was focused on identification of health risks of the organic air pollution mixtures with the emphasis on genotoxicity (SOS chromotest, -S9/+S9and a dioxin toxicity (cell-line H4IIE.luc). The organic extracts of TSP and fine particles were studied. Genotoxicity was caused mainly by direct genotoxins that are bound in larger particles. Progenotoxic compounds were mainly in the fine particles. The dioxin toxicity is related mainly to PAHs. The results showed that the derivatives of PAHs were responsible for a significant part of the toxic potency of the organic air pollution. A part of them is bound in the non-respirable particle
Czech name
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Czech description
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Project
<a href="/en/project/SJ%2F740%2F2%2F01" target="_blank" >SJ/740/2/01: Transformation of air pollutants concerning negative anthropogenic process, their impacts on human population, landscape receptors and simulation their transport in athmosphere.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Setac Europe, 14th Annual Meeting Prague, Czech Republic 18.4. - 22.4.2004
ISBN
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ISSN
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e-ISSN
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Number of pages
1
Pages from-to
184-184
Publisher name
MZP
Place of publication
Praha
Event location
Praha
Event date
Apr 18, 2004
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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