Response of normal vs. cancer colon cells to short- and long-chain fatty acids
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F08%3A00060308" target="_blank" >RIV/00216224:14310/08:00060308 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Response of normal vs. cancer colon cells to short- and long-chain fatty acids
Original language description
Dynamic balance between proliferation, differentiation and apoptosis is necessary for healthy intestinal epithelium. Together with endogenous regulators dietary lipid compounds like esential polyunsaturated fatty acids (PUFAs) and short chain fatty acid? butyrate (produced by microbial fermentation of fibre) can play an important role in maintaining homeostasis in this tissue. Signals induced by these factors are integrated inside the cells and may have significant impact on cell metabolism and kinetics. Processes of colon cell differentiation and apoptosis are accompanied with changes of biophysical properties of cell membranes, and by modulation of constitution, structure, symmetry and metabolism of cell lipids.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2008
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů