STUDY OF APPLICATIONS OF CATION-EXCHANGER RESINS FOR DIRECT N-MONOACYLATION ON PIPERAZINE
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F10%3A00040195" target="_blank" >RIV/00216224:14310/10:00040195 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
STUDY OF APPLICATIONS OF CATION-EXCHANGER RESINS FOR DIRECT N-MONOACYLATION ON PIPERAZINE
Original language description
Direct N-monoacylation of piperazine was already described for its reaction with acyl chlorides or alkyl chlorocarbonates in acidified water (pH ca 3) with very bad yields - about 30 % of monoacyl piperazine. On the other hand, direct N-mono-benzylationof piperazine in the piperazinium chloride form by benzyl chloride in ethanol provides mono-product in excellent yield. N-monoacyl piperazines can be key building block in industrial piperazine chemistry, better than N-monobenzyl piperazine on the groundof facile deacylation. Possibilities for an application of cation-exchanger resins for better than described direct N-monoacylation reactions on piperazine by an action of different acylating agents in polar organic solvents were studied. For study bothtypes of resins, i. e. strong acid (sulfonated polystyrene-divinylbenzene copolymer) and weak acid (acrylic acid-divinylbenzene copolymer) as cation-exchanger resins were used.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/2A-1TP1%2F090" target="_blank" >2A-1TP1/090: New catalysts and reagents for sustainable green syntheses and combinatorial syntheses</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach<br>V - Vyzkumna aktivita podporovana z jinych verejnych zdroju<br>N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
XXIVth EUROPEAN COLLOQUIUM on HETEROCYCLIC CHEMISTRY
ISBN
978-3-9502992-0-5
ISSN
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e-ISSN
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Number of pages
2
Pages from-to
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Publisher name
Book-of-Abstracts.com
Place of publication
Vienna, Austria
Event location
Vienna
Event date
Jan 1, 2010
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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