Unusual Interstrand Pt(S,S-diaminocyclohexane)-GG Crosslink Formed by Rearrangement of a Classical Intrastrand Crosslink Within a DNA Duplex
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F10%3A00043383" target="_blank" >RIV/00216224:14310/10:00043383 - isvavai.cz</a>
Alternative codes found
RIV/60077344:_____/10:00342964 RIV/60076658:12310/10:00011900
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Unusual Interstrand Pt(S,S-diaminocyclohexane)-GG Crosslink Formed by Rearrangement of a Classical Intrastrand Crosslink Within a DNA Duplex
Original language description
An unusual G6G11 interstrand crosslink is formed by spontaneous rearrangement of the canonical G5G6 intrastrand crosslink generated from the DNA duplex d(CCTTG5G6T7C8TC)-d(G11AGACCAAGG) and Pt(S,S-di-aminocyclohexane)2+ (the enantiomer of the antitumor drug oxaliplatin). The final product provides a rare example of intramolecular self-intercalation of DNA.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GP202%2F08%2FP416" target="_blank" >GP202/08/P416: NMR study of interaction of cisplatined G/T mismatched DNA substrate with protein MutS</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chemistry - An Asian Journal
ISSN
1861-4728
e-ISSN
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Volume of the periodical
5
Issue of the periodical within the volume
2
Country of publishing house
DE - GERMANY
Number of pages
4
Pages from-to
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UT code for WoS article
000274539100003
EID of the result in the Scopus database
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