Nematode infection model for testing of innate immunity in Drosophila

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F11%3A00049852" target="_blank" >RIV/00216224:14310/11:00049852 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Nematode infection model for testing of innate immunity in Drosophila
Original language description
Entomopathogenic nematodes (EPN?s) of the genera Heterorhabditis are obligate and lethal insect parasites. In recent years they have been used increasingly as biological control agents. Infective juveniles occur free living in the soil and are capable ofseeking out hosts and penetrate them through the cuticle or natural orifices. EPN?s are symbiotically associated with bacteria of the genera Photorhabdus. The bacterial symbionts are essential to kill the host (within 24-48 hours) and digest host tissues. The tripartite model (Drosophila, nematodes, bacteria) was recently established and used for determination of immune factors against nematode infection. Drosophila larvae are more resistant to nematode infection than Galleria mellonella (insect used for laboratory nematode rearing), but both can be used as natural infection model.
Czech name
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Czech description
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Project
<a href="/en/project/GP206%2F09%2FP470" target="_blank" >GP206/09/P470: The influence of the eicosanoid biosynthesis inhibitors to immunity of the wax moth Galleria mellonella</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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