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Cryptochrome 2 necessary for magnetosensitivity of American cockroach P. americana

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F11%3A00050059" target="_blank" >RIV/00216224:14310/11:00050059 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Cryptochrome 2 necessary for magnetosensitivity of American cockroach P. americana

  • Original language description

    There are many new insights about how the animal sense for geomagnetic field might work ? whether based on magnetic particles in tissues or on light perception in visual pathway - but the exact mechanism of reception and transmission has not yet been clarified. In our work, we addressed the question of the role of Cryptochrome in compass sense of insects. Cryptochromes (CRYs) are molecules found in retina both vertebrates and invertebrates - among other things directly involved in controlling of circadian rhythms. In our tests, we worked with a cockroach Periplaneta americana which has the only vertebrate-like type of cryptochrom, CRY2. We combined molecular genetic approaches (RNAi gene silencing) with a behavioral assay (studying movement activity ofcockroaches in changing magnetic field). Cockroaches were injected with CRY dsRNA and, 15 days later, they underwent an assay. Treated animals not only lost their circadian rhythmicity, but they were not able to perceive the magnetic fie

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GC206%2F07%2FJ041" target="_blank" >GC206/07/J041: Towards the neuronal basis of insect magnetoreception.</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů