Cryptochrome 2 necessary for magnetosensitivity of American cockroach P. americana
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F11%3A00050059" target="_blank" >RIV/00216224:14310/11:00050059 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Cryptochrome 2 necessary for magnetosensitivity of American cockroach P. americana
Original language description
There are many new insights about how the animal sense for geomagnetic field might work ? whether based on magnetic particles in tissues or on light perception in visual pathway - but the exact mechanism of reception and transmission has not yet been clarified. In our work, we addressed the question of the role of Cryptochrome in compass sense of insects. Cryptochromes (CRYs) are molecules found in retina both vertebrates and invertebrates - among other things directly involved in controlling of circadian rhythms. In our tests, we worked with a cockroach Periplaneta americana which has the only vertebrate-like type of cryptochrom, CRY2. We combined molecular genetic approaches (RNAi gene silencing) with a behavioral assay (studying movement activity ofcockroaches in changing magnetic field). Cockroaches were injected with CRY dsRNA and, 15 days later, they underwent an assay. Treated animals not only lost their circadian rhythmicity, but they were not able to perceive the magnetic fie
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GC206%2F07%2FJ041" target="_blank" >GC206/07/J041: Towards the neuronal basis of insect magnetoreception.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů