Voltametrická studie cytosinových oligonukleotidů v pufrovaném a nepufrovaném prostředí
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F11%3A00052416" target="_blank" >RIV/00216224:14310/11:00052416 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Voltametrická studie cytosinových oligonukleotidů v pufrovaném a nepufrovaném prostředí
Original language description
The work deals with the electrochemical study of three short homo?deoxyoligonucleotides (homo?ODNs) containing cytosine (C). Using linear sweep voltammetry (LSV) and elimination voltammetry with linear scan (EVLS) the effect of pH and the number of C inthe ODN chain on reduction signals of dC3, dC6, and dC9 in buffered and non-buffered solutions was investigated. Reduction C peaks, recorded at mercury electrode in the potential range from ?1.1 V to ?1.7 V vs. Ag/AgCl/3M KCl, are strongly dependent notonly on pH but also on the composition of solutions. With the addition of buffer (acetate-phosphate buffer) to 0.1 M NaCl the reduction peaks increase and move to more positive potentials. In non-buffered solutions changes of voltammetric responses of all ODNs in time were observed. The biggest changes were recorded in the case of dC6. The adsorption or surface kinetics of ODNs was confirmed by EVLS and electrochemical behaviour of ODNs studied was discussed in the context of the i-motif
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LC06035" target="_blank" >LC06035: Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
XXXI. MODERNÍ ELEKTROCHEMICKÉ METODY
ISBN
978-80-254-9634-3
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
16-19
Publisher name
BEST Servis
Place of publication
Ústí nad Labem
Event location
Jetřichovice
Event date
Jan 1, 2011
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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