ELECTROCHEMICAL STUDY OF SHORT CYTOSINE OLIGONUCLEOTIDES

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F12%3A00057421" target="_blank" >RIV/00216224:14740/12:00057421 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
ELECTROCHEMICAL STUDY OF SHORT CYTOSINE OLIGONUCLEOTIDES
Original language description
Cytosine-rich oligodeoxynucleotides (C-rich ODNs) play diverse roles in the regulation of protein expression at both transcriptional and translational levels. A repetitive C sequence can be responsible for some diseases. It is commonly known that C-richODNs form the stable i-motif structure, interesting due to a crucial role in the process of genetic information transfer. The aim of this contribution is to find out the relationship between the structure of homo-ODNs in buffered solutions with the sameionic strength (I = 0.18 M) but with a different number of cytosines (dCx; x = 3, 4, 5, 6, 9). Using linear sweep voltammetry (LSV) and elimination voltammetry with linear scan (EVLS), electrochemical reduction signals studied on a mercury electrode reflect the conformation changes of the C-rich ODN chain.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
XII. Pracovní setkání fyzikálních chemiků a elektrochemiků
ISBN
9788073756185
ISSN
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e-ISSN
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Number of pages
2
Pages from-to
64-65
Publisher name
Mendelova univerzita v Brně
Place of publication
Brno
Event location
Brno
Event date
Jan 1, 2012
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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