Solution Behavior of DOTP Analogs and Their Lanthanide(III) Complexes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F11%3A00054681" target="_blank" >RIV/00216224:14310/11:00054681 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Solution Behavior of DOTP Analogs and Their Lanthanide(III) Complexes
Original language description
Complexes of trivalent lanthanides are utilized in medicine and preclinical research as magnetic resonance, optical or nuclear probes. In this contribution, thermodynamic (ligand dissociation and complex stability constants) and kinetic (formation and dissociation) properties of selected lanthanide(III) complexes with phosphorus-containing macrocyclic ligand which are based on cyclen skeleton will be presented. The ligands are H8dotp analogs where substituents modified on all parent phosphonate groups are monoester (H4dotpOEt), phosphinate (H4dotpH) or phenylphosphinate (H4dotpPh). The H8dotp analogs are less basic then the mother ligand and, consequently, the thermodynamic stabilities of the lanthanide(III) complexes are much lower. Rates of the complex formation of studied ligands are of the same order of magnitude to that for H8dotp. Kinetic inertness of complexes of the anologs is mostly lower; however, the kinetic inerteness is still much higher than that of complexes of open-chai
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CA - Inorganic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ME09065" target="_blank" >ME09065: Research of new detection systems based on sensor arrays for application in speciation analysis</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů