Cell motility in marine early emerging apicomplexans

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F12%3A00058218" target="_blank" >RIV/00216224:14310/12:00058218 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/14:00101823
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Cell motility in marine early emerging apicomplexans
Original language description
Apicomplexans represent one of the most successful and diverse group of unicellular parasites exhibiting unique adaptations to their life style. Many of them are causative agents for major human diseases (such as malaria, toxoplasmosis and cryptosporidiosis), which are still poorly controlled and require development of novel sustainable therapies. The apicomplexan cytoskeletal elements play an important role in various life processes and thus they represent a potential target for chemotherapeutic intervention. Their highly motile invasive zoites use a unique conserved form of actin-based gliding motility for movement, host cell invasion and tissue traversal. Our intent is to investigate if the glideosome concept, proposed in Toxoplasma, could be also applied to basal lineages of Apicomplexa. We focus on deep-branching groups, especially gregarines and protococcidians, restricted to invertebrates (Diakin et al. 2012).
Czech name
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Czech description
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Project
<a href="/en/project/GBP505%2F12%2FG112" target="_blank" >GBP505/12/G112: ECIP - European Centre of Ichtyoparasitology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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