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Motility of Siedleckia nematoides (Apicomplexa): Structural changes of cytoskeletal structures after drugs application

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00073865" target="_blank" >RIV/00216224:14310/14:00073865 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Motility of Siedleckia nematoides (Apicomplexa): Structural changes of cytoskeletal structures after drugs application

  • Original language description

    Apicomplexans belong to the most monitored group of Protista, comprising exclusively parasites of vertebrates and invertebrates. Phylum Apicomplexa is characterised by typical apical complex and a complicated cell cortex consisting of inner membrane complex (IMC) underlying the plasma membrane. The IMC is connected with numerous cytoskeletal elements such as actomyosin complex, microtubules and a network of intermediate filaments. Numerous studies report that the motile apicomplexan invasive stages, theso-called zoites, use a unique mechanism of substrate dependent gliding motility facilitated by a conserved form of actomyosin motor (the so called ?glideosome? concept). This concept was first time described in Toxoplasma gondii. The gliding motility relies on dynamic turnover of actin. Similarly apicomplexan myosins are considered unconventional and form a new class (XIV).

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    EG - Zoology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GBP505%2F12%2FG112" target="_blank" >GBP505/12/G112: ECIP - European Centre of Ichtyoparasitology</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů