Variability, structure and selection of MHCIIB genes in Chondrostoma toxostoma and Chondrostoma nasus in hybrid zones

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F12%3A00058586" target="_blank" >RIV/00216224:14310/12:00058586 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Variability, structure and selection of MHCIIB genes in Chondrostoma toxostoma and Chondrostoma nasus in hybrid zones
Original language description
To characterise the overall genetic diversity, population structure and selection processes in cyprinid fish, MHC genes of IIB class have been analyzed. As the model organism in this study, two congeneric cyprinids, the introduced Chondrostoma nasus andnative, protected and endemic C. toxostoma that live in sympatry and form a hybrid zone in the Durance River (South France, Mediterranean Sea drainage) were studied. For the individual determination (pure species versus hybrid) all fish were genotyped for mtDNA (cyt b) and 41 microsatellite loci. The allelic variability in exon 2 of two MHCIIB genes (DAB1-like and DAB3-like) representing the most variable region with the nonsynonymous sites specifying the peptide binding region was analysed. The resultsreveal the non uniform allele expression within individuals, duplication of both studied loci (previously showed in several cyprinid species) and that the exon 2 of DAB genes is subjected to positive selection.
Czech name
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Czech description
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Project
<a href="/en/project/GAP505%2F10%2F1138" target="_blank" >GAP505/10/1138: Host-parasite interactions in hybrid systems of cyprinid fish</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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