QUANTUM DOTS AND THEIR INTERACTIONS WITH BIOMOLECULES

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F12%3A00060130" target="_blank" >RIV/00216224:14310/12:00060130 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
QUANTUM DOTS AND THEIR INTERACTIONS WITH BIOMOLECULES
Original language description
Semiconductor quantum dots (QDs) coated with thioalkyl acid ligands are often used as probes and reporters for nucleic acid sensing, or protein sensing using aptamers, and are also potential vectors for gene delivery. In such applications, the interactions that potentially lead to the adsorption of oligonucleotides onto the surface of colloidal QDs are an important consideration. The interaction between Beta-sheet breaker prion protein and CdTe quantum dots (QDs) was studied by differential pulse voltammetry connected with adsorptive transfer stripping technique. Results showed that the electrochemical signals of prion protein were strongly quenched by CdTe QDs. This phenomenon can be considered as a first step of suggesting of a biosensor for determination of prions in real samples without a sample pre-treatment.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
XII. Pracovní setkání fyzikálních chemiků a elektrochemiků. Sborník příspěvků.
ISBN
9788073756185
ISSN
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e-ISSN
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Number of pages
2
Pages from-to
237-238
Publisher name
Mendelova univerzita v Brně
Place of publication
Brno
Event location
Brno
Event date
Jan 1, 2012
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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