Synthesis, activity and interaction of nitrone functionalized PAH derivatives
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F13%3A00066251" target="_blank" >RIV/00216224:14310/13:00066251 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Synthesis, activity and interaction of nitrone functionalized PAH derivatives
Original language description
Polycyclic aromatic hydrocarbons (PAHs) are widely studied. Their carcinogenic properties are well known. In a sharp contrast to those effects the functionalized PAHs were recently identified as important candidates for cancer therapy.1 Mechanism of action is often simplified and studied at the DNA level. A lot of discussion has been held about groups being introduced to the PAHs structure. Novel approach to functionalized polycyclic aromatic hydrocarbons (PAHs) is presented. According to our experiencein nitrone chemistry2 the synthetic design of new PAHs derivatives was achieved by a multicomponent reaction of compounds 1-3.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA203%2F09%2F1345" target="_blank" >GA203/09/1345: Allenyl synthon in synthesis of heterocyclic compounds</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů