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Electron microscopic visualization of alterations in rodent gastric tissue induced by Cryptosporidium muris

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F13%3A00066917" target="_blank" >RIV/00216224:14310/13:00066917 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    čeština

  • Original language name

    Electron microscopic visualization of alterations in rodent gastric tissue induced by Cryptosporidium muris

  • Original language description

    The phylum Apicomplexa includes significant unicellular parasites of humans and animals. One of these is the genus Cryptosporidium that is the causative agent of zoonotic disease of the gastrointestinal and respiratory tract, called cryptosporidiosis. This study compares the progress of Cryptosporidium muris infection in gastric tissue of laboratory rodents, BALB/c mice and Mastomys coucha. The glandular and non-glandular parts of stomach were examined at selected time points after oral inoculation witha dose of 106 infective oocysts of C. muris. Rodents exhibited significant differences in responses to the parasitisation as well as in chronology of pathological changes of gastric tissue induced by the parasite. The sequence of individual changes during the acute phase of parasitisation, however, corresponded in both hosts.

  • Czech name

    Electron microscopic visualization of alterations in rodent gastric tissue induced by Cryptosporidium muris

  • Czech description

    The phylum Apicomplexa includes significant unicellular parasites of humans and animals. One of these is the genus Cryptosporidium that is the causative agent of zoonotic disease of the gastrointestinal and respiratory tract, called cryptosporidiosis. This study compares the progress of Cryptosporidium muris infection in gastric tissue of laboratory rodents, BALB/c mice and Mastomys coucha. The glandular and non-glandular parts of stomach were examined at selected time points after oral inoculation witha dose of 106 infective oocysts of C. muris. Rodents exhibited significant differences in responses to the parasitisation as well as in chronology of pathological changes of gastric tissue induced by the parasite. The sequence of individual changes during the acute phase of parasitisation, however, corresponded in both hosts.

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    EG - Zoology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GPP506%2F10%2FP372" target="_blank" >GPP506/10/P372: Comparative morphology and immunohistochemistry in the evaluation of phylogenetic affinities among early emerging apicomplexans</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů