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Exploring the cystatins of helminths

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00073668" target="_blank" >RIV/00216224:14310/14:00073668 - isvavai.cz</a>

  • Alternative codes found

    RIV/62157124:16170/14:43873313

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Exploring the cystatins of helminths

  • Original language description

    Parasitic organisms release numerous types of molecules essential for their survival. Cystatins - cysteine peptidase inhibitors (CPI) were determined as important protein molecules which participate in the processes in the host-parasite interface. Theireffect can influence the host immune response, particularly the processing and presentation of antigens, production of nitric oxide, etc. The aim of our study is to expand the information about cystatins produced by helminths and to reveal their functions in four selected parasitic model species representing the major groups of helminths. We used bioinformatic tools to analyze the transcriptomic and/or genomic data of Eudiplozoon nipponicum (Monogenea), Hymenolepis diminuta (Cestoda), Fascioloides magna(Trematoda) and Trichinella spiralis (Nematoda) and we searched for the presence of conserved cystatin domains.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    EG - Zoology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů