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The Staphylococcal Cassette Chromosome mec type V from Staphylococcus aureus ST398 is packaged into bacteriophage capsids

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00073787" target="_blank" >RIV/00216224:14310/14:00073787 - isvavai.cz</a>

  • Result on the web

    <a href="http://www.sciencedirect.com/science/article/pii/S1438422114000617" target="_blank" >http://www.sciencedirect.com/science/article/pii/S1438422114000617</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.ijmm.2014.05.010" target="_blank" >10.1016/j.ijmm.2014.05.010</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The Staphylococcal Cassette Chromosome mec type V from Staphylococcus aureus ST398 is packaged into bacteriophage capsids

  • Original language description

    The Staphylococcal Cassette Chromosome mec (SCCmec) confers methicillin resistance to Staphylococcus aureus. While SCCmec is generally regarded as a mobile genetic element, the precise mechanisms by which large SCCmec elements are exchanged between staphylococci have remained enigmatic. In the present studies, we observed that the clinical methicillin-resistant S. aureus (MRSA) isolate UMCG-M4 with the sequence type 398 contains four prophages belonging to the serological groups A, B and Fa. Previous studies have shown that certain serological group B bacteriophages of S. aureus are capable of generalized transduction. We therefore assessed the transducing capabilities of the phages from strain UMCG-M4. The results show that some of these phages can indeed transduce plasmid pT181 to the recipient S. aureus strain RN4220. Therefore, we also investigated the possible involvement of these transducing phages in the transmission of the large SCCmec type V (5C2&amp;5) element of S. aureus UM

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GP13-05069P" target="_blank" >GP13-05069P: Horizontal transfer of Staphylococcal Cassette Chromosome mec (SCCmec) elements mediated by bacteriophages across the Staphylococcus strains</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Medical Microbiology

  • ISSN

    1438-4221

  • e-ISSN

  • Volume of the periodical

    304

  • Issue of the periodical within the volume

    5-6

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    11

  • Pages from-to

    764-774

  • UT code for WoS article

    000339775600030

  • EID of the result in the Scopus database