Determination of binding constant of 1st generation antidiabetic drug with human serum albumin
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00074050" target="_blank" >RIV/00216224:14310/14:00074050 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Determination of binding constant of 1st generation antidiabetic drug with human serum albumin
Original language description
The capillary electrophoresis fontal analysis (CE-FA) was used to study the affinities between selected 1st generation antidiabetic drugs (tolbutamide, chlorpropamide) and human serum albumin (HSA). The binding constant (Kb) was measured under physiological conditions. The log Kb values obtained by means of CE-FA have a good repeatability (RSD < 3%).
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GBP206%2F12%2FG014" target="_blank" >GBP206/12/G014: Center for advanced bioanalytical technologies</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
11 th International Interdisciplinary Meeting on Bioanalysis CECE 2014
ISBN
9788090495920
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
325-327
Publisher name
Institute of Analytical Chemistry AS CR, v. v. i., Brno, Česká republika
Place of publication
Brno
Event location
Brno
Event date
Oct 20, 2014
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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