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Determination of binding constant of 1st generation antidiabetic drug with human serum albumin

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00074050" target="_blank" >RIV/00216224:14310/14:00074050 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Determination of binding constant of 1st generation antidiabetic drug with human serum albumin

  • Original language description

    The capillary electrophoresis fontal analysis (CE-FA) was used to study the affinities between selected 1st generation antidiabetic drugs (tolbutamide, chlorpropamide) and human serum albumin (HSA). The binding constant (Kb) was measured under physiological conditions. The log Kb values obtained by means of CE-FA have a good repeatability (RSD &lt; 3%).

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GBP206%2F12%2FG014" target="_blank" >GBP206/12/G014: Center for advanced bioanalytical technologies</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    11 th International Interdisciplinary Meeting on Bioanalysis CECE 2014

  • ISBN

    9788090495920

  • ISSN

  • e-ISSN

  • Number of pages

    3

  • Pages from-to

    325-327

  • Publisher name

    Institute of Analytical Chemistry AS CR, v. v. i., Brno, Česká republika

  • Place of publication

    Brno

  • Event location

    Brno

  • Event date

    Oct 20, 2014

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article