Study of competitive binding between diclofenac and tryptophan on hunam serum albumin using capillary electrophoresis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00074051" target="_blank" >RIV/00216224:14310/14:00074051 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Study of competitive binding between diclofenac and tryptophan on hunam serum albumin using capillary electrophoresis
Original language description
The capillary electrophoresis fontal analysis (CE-FA) was used to study the affinities between diclofenac and tryptophan, and human serum albumin (HSA). Apparent log Kb = (4.4 ? 0.01) L/mol for diclofenac?HSA and log Kb = (3.95 ? 0.004) L/mol for tryptophan?HSA have a good repeatability. The displacement experiment shows the displacement of tryptophan from binding site using diclofenac.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GBP206%2F12%2FG014" target="_blank" >GBP206/12/G014: Center for advanced bioanalytical technologies</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
11 th International Interdisciplinary Meeting on Bioanalysis CECE 2014.
ISBN
9788090495920
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
340-342
Publisher name
Institute of Analytical Chemistry AS CR, v. v. i., Brno, Česká republika
Place of publication
Brno
Event location
Brno
Event date
Oct 20, 2014
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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