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Study of competitive binding between diclofenac and tryptophan on hunam serum albumin using capillary electrophoresis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00074051" target="_blank" >RIV/00216224:14310/14:00074051 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Study of competitive binding between diclofenac and tryptophan on hunam serum albumin using capillary electrophoresis

  • Original language description

    The capillary electrophoresis fontal analysis (CE-FA) was used to study the affinities between diclofenac and tryptophan, and human serum albumin (HSA). Apparent log Kb = (4.4 ? 0.01) L/mol for diclofenac?HSA and log Kb = (3.95 ? 0.004) L/mol for tryptophan?HSA have a good repeatability. The displacement experiment shows the displacement of tryptophan from binding site using diclofenac.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GBP206%2F12%2FG014" target="_blank" >GBP206/12/G014: Center for advanced bioanalytical technologies</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    11 th International Interdisciplinary Meeting on Bioanalysis CECE 2014.

  • ISBN

    9788090495920

  • ISSN

  • e-ISSN

  • Number of pages

    3

  • Pages from-to

    340-342

  • Publisher name

    Institute of Analytical Chemistry AS CR, v. v. i., Brno, Česká republika

  • Place of publication

    Brno

  • Event location

    Brno

  • Event date

    Oct 20, 2014

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article