Patterns of selection on Plasmodium falciparum erythrocyte binding antigens after the colonisation of the New World
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00075087" target="_blank" >RIV/00216224:14310/14:00075087 - isvavai.cz</a>
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1111/mec.12696/abstract" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/mec.12696/abstract</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/mec.12696" target="_blank" >10.1111/mec.12696</a>
Alternative languages
Result language
angličtina
Original language name
Patterns of selection on Plasmodium falciparum erythrocyte binding antigens after the colonisation of the New World
Original language description
Pathogens, which have recently colonized a new host species or new populations of the same host, are interesting models for understanding how populations may evolve in response to novel environments. During its colonization of South America from Africa Plasmodium falciparum, the main agent of malaria, has been exposed to new conditions in distinctive new human populations (Amerindian and populations of mixed origins), that likely exerted new selective pressures on the parasite's genome. Among the genesthat might have experienced strong selective pressures in response to these environmental changes, the eba genes (erythrocyte binding antigens genes), which are involved in the invasion of the human red blood cells, constitute good candidates. In this study, we analyzed, in South America, the polymorphism of three eba genes (eba-140, eba-175, eba-181) and compared it to the polymorphism observed in African populations.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EG - Zoology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/EE2.3.30.0009" target="_blank" >EE2.3.30.0009: Employment of Newly Graduated Doctors of Science for Scientific Excellence</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Molecular Ecology
ISSN
0962-1083
e-ISSN
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Volume of the periodical
23
Issue of the periodical within the volume
8
Country of publishing house
US - UNITED STATES
Number of pages
15
Pages from-to
1979-1993
UT code for WoS article
000333858200008
EID of the result in the Scopus database
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