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Conformational dimorphism of isochroman-1-ones in the solid state

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00078569" target="_blank" >RIV/00216224:14310/14:00078569 - isvavai.cz</a>

  • Alternative codes found

    RIV/70883521:28610/14:43871827 RIV/70883521:28110/14:43871827

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.molstruc.2014.03.005" target="_blank" >http://dx.doi.org/10.1016/j.molstruc.2014.03.005</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.molstruc.2014.03.005" target="_blank" >10.1016/j.molstruc.2014.03.005</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Conformational dimorphism of isochroman-1-ones in the solid state

  • Original language description

    Isochroman-1-one derivatives, which are relatives of coumarins, display a broad spectrum of biological activity; therefore, these derivatives attract the attention of chemists. A series of new isochroman-1-ones were prepared by the reaction of benzyl-derived Grignard reagents with acyl chlorides. All of the prepared compounds were characterized using single-crystal X-ray diffraction as well as FT-IR, NMR and MS techniques. Single crystal X-ray diffraction analysis revealed that the isochromanones can adopt two distinct conformations in the solid state. For one of the compounds, two polymorphs with unique forms crystallized separately under different temperatures. The packing of all of the examined crystals is stabilized via weak intramolecular C-H center dot center dot center dot pi and/or C-H center dot center dot center dot O interactions.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Molecular Structure

  • ISSN

    0022-2860

  • e-ISSN

  • Volume of the periodical

    1078

  • Issue of the periodical within the volume

    december

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    8

  • Pages from-to

    106-113

  • UT code for WoS article

    000343845100012

  • EID of the result in the Scopus database