Effect of alkali metal ions on dissociation kinetics of Cu(II) complexes of DOTP-like macrocyclic ligands
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F15%3A00081670" target="_blank" >RIV/00216224:14310/15:00081670 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Effect of alkali metal ions on dissociation kinetics of Cu(II) complexes of DOTP-like macrocyclic ligands
Original language description
Tetraaza-macrocyclic ligands based on cyclen skeleton are well known for their great ability to bind copper(II) ion leading to formation of metal complexes of high thermodynamic stability and kinetic inertness which are required for their in vivo applications and in medicine. Some complexes of copper radioisotopes are utilized in diagnosis (positron emission tomography - PET, 64Cu with half-life 12.8 h) or in radio-immunotherapy (67Cu with half-life 62 h). In addition, the sodium and potassium ions playan important role in biology, e.g. concentration gradient of sodium/potassium ions is important in living organism for many cell functions, and their presence in the solution can affect the kinetic inertness of copper(II) complexes. In this work, the acid-assisted dissociation kinetics of Cu(II) complexes with DOTP-like ligands (e.g. H6do3p, H6do3p1ol, H8dotp) was studied by means of molecular absorption spectroscopy in presence of Li+, Na+ and K+ salts employed as supporting electrolyt
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CA - Inorganic chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Acta of the International Symposia on Metal Complexes ? ISMEC Acta vol. 5 (2015)
ISBN
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ISSN
2239-2459
e-ISSN
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Number of pages
2
Pages from-to
118-119
Publisher name
University of Wroclaw
Place of publication
Wroclaw
Event location
Wroclaw
Event date
Jan 1, 2015
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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