Use of flower-like gold nanoparticles in time-of-flight mass spectrometry
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F15%3A00083213" target="_blank" >RIV/00216224:14310/15:00083213 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/rcm.7265" target="_blank" >http://dx.doi.org/10.1002/rcm.7265</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/rcm.7265" target="_blank" >10.1002/rcm.7265</a>
Alternative languages
Result language
angličtina
Original language name
Use of flower-like gold nanoparticles in time-of-flight mass spectrometry
Original language description
Many kinds of nanoparticles (NPs) have been used for mass spectrometry (MS) so far. Here we report the first use of flower-like gold nanoparticles (AuNPs) as a mediator enhancing ionization in MS of peptides and proteins. Flower-like AuNPs were characterized using transmission and scanning electron microscopy, UV-VIS spectrophotometry, and laser desorption/ionization (LDI) MS and compared with polyhedral AuNPs. Mass spectra were obtained in positive ion mode using time-of-flight (TOF) analyzer coupled with either matrix assisted laser desorption/ionization (MALDI) or surface assisted laser desorption/ionization (SALDI) methods. The intensities of peptide peaks (m/z 500?3500) were up to 7.5x and up to 7x higher using flower-like AuNPs and flower-like AuNPs-enriched cyano-4-hydroxycinnamic acid (CHCA) matrix respectively, than the classical CHCA matrix.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
<a href="/en/project/EE2.3.20.0185" target="_blank" >EE2.3.20.0185: Centre for analysis and modeling of tissues and organs</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Rapid Communication in Mass Spectrometry
ISSN
0951-4198
e-ISSN
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Volume of the periodical
29
Issue of the periodical within the volume
17
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
1585-1595
UT code for WoS article
000360761300006
EID of the result in the Scopus database
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