Stable Gelatin Nanofibers Modified with Oxidized Cellulose for Soft Tissue Engineering
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F15%3A00086961" target="_blank" >RIV/00216224:14310/15:00086961 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26310/15:PU115578
Result on the web
<a href="http://www.fch.vutbr.cz/media/chl_2015/images/BoA_CHL2015.pdf" target="_blank" >http://www.fch.vutbr.cz/media/chl_2015/images/BoA_CHL2015.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Stable Gelatin Nanofibers Modified with Oxidized Cellulose for Soft Tissue Engineering
Original language description
The present work deals with the preparation of (bio) polymer nanofibers by Nanospider technology. The obtained nanofibers are biocompatible, bioadhesive, porous and mimic the structure of the extracellular matrix forming the structure of tissues. Gelatinnanofibers modified by addition of sodium or calcium salt of oxidized cellulose were successfully prepared. Gelatin is a biocompatible and biodegradable polymer. Oxidized cellulose and its salts are biocompatible, biodegradable and they also exhibit hemostatic and bactericidal efficiency. Crosslinking process was an another important step to improve hydrolytic stability and mechanical properties of nanofibers. H441 cell lines (human papillary adenocarcinoma cells) were seeded on prepared electrospun nanofibers. The viability of H441 cell lines on nanofibers was evaluated. Newly prepared material may have a potential application in surgery and regenerative medicine of soft tissues (e. g. decubitus and burns).
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
BL - Plasma physics and discharge through gases
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů