Novel Oxycellulose/Gelatin Nanofibers for Medical Applications

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F15%3A00086963" target="_blank" >RIV/00216224:14310/15:00086963 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26310/15:PU116720
Result on the web
<a href="http://www.fch.vutbr.cz/media/sok/sbornik_prispevku_2015.pdf" target="_blank" >http://www.fch.vutbr.cz/media/sok/sbornik_prispevku_2015.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Novel Oxycellulose/Gelatin Nanofibers for Medical Applications
Original language description
Novel hydrolytically stable gelatin nanofibers were modified with sodium or calcium salts of oxidized cellulose (oxycellulose) to enhance nanofibers? stability and bactericidal efficiency. The unique inhibitory effect of the electrospun gelatin/ oxycellulose nanofibers against pathogenic bacteria was examined by luminometric method using modified bioluminescence of E. coli strain. Non-woven nanofiber fabric has been tested for its biocompatibility using human lung adenocarcinoma cells line NCI-H441. Cells cultured on nanofibrous materials firmly adhered to their surface without the changing in shape, as determined by scanning electron microscopy, and did not show any signs of dying as revealed by live/death staining via fluorescence microscope. This newly developed nanofibrous material seeded with NCI-H441 cell line could be therefore used as a platform for lung disease modeling and anti-cancer drug testing.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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