MEKC LIF method for analysis of amino acids after on-capillary derivatization by transverse diffusion of laminar flow profiles mixing of reactants for assessing developmental capacity of human embryos after in vitro fertilization
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F16%3A00087859" target="_blank" >RIV/00216224:14310/16:00087859 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/16:00066191
Result on the web
<a href="http://dx.doi.org/10.1002/elps.201500587" target="_blank" >http://dx.doi.org/10.1002/elps.201500587</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/elps.201500587" target="_blank" >10.1002/elps.201500587</a>
Alternative languages
Result language
angličtina
Original language name
MEKC LIF method for analysis of amino acids after on-capillary derivatization by transverse diffusion of laminar flow profiles mixing of reactants for assessing developmental capacity of human embryos after in vitro fertilization
Original language description
Evaluating the physiological state of an organism is of clinical importance. In assisted reproduction, knowledge of the embryo’s physiology is crucial for selecting the embryo with the highest developmental capacity to ensure high pregnancy rates. Amino acids (AAs) are involved in many biochemical processes during embryo development, which means that the determination of AA fluctuations in the embryo’s surroundings can determine the embryo’s physiological state. Since current embryo selection methods are mainly based on visual assessment, which lacks proper accuracy, a novel method for the analysis of AAs in the embryo’s surroundings was developed. AAs were analyzed by means of MEKC-LIF after on capillary derivatization by naphthalene 2,3 dicarboxaldehyde. The reactants were injected under the three zone arrangement and mixed using the transverse diffusion of laminar flow profiles methodology.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GAP206%2F11%2F0009" target="_blank" >GAP206/11/0009: Capillary electrophoresis as a member of the metabolomic analytical toolbox</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electrophoresis
ISSN
0173-0835
e-ISSN
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Volume of the periodical
37
Issue of the periodical within the volume
17-18
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
2305-2312
UT code for WoS article
000383596800004
EID of the result in the Scopus database
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