On-line capillary electrophoretic method for kinetic and inhibition studies of beta-secretase
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F16%3A00088481" target="_blank" >RIV/00216224:14310/16:00088481 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
On-line capillary electrophoretic method for kinetic and inhibition studies of beta-secretase
Original language description
Alzheimer’s disease (AD) represents the most common cause of dementia. According to amyloid cascade hypothesis, pathogenesis of the disease could be slowed down or even stopped by inhibition of beta-secretase. On-line capillary electrophoretic methods represent a promising tool for screening of the enzyme’s activity. A generic on-line CE method for kinetic and inhibition studies of BACE was therefore introduced.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA16-06106S" target="_blank" >GA16-06106S: Capillary electrophoresis based high-throughput system for beta-secretase inhibitor screening as a therapeutic target of Alzheimer's disease</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
CECE 2016
ISBN
9788090495944
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
227-229
Publisher name
Institute of Analytical Chemistry of the CAS, v. v. i., Brno, Czech Republic
Place of publication
Brno
Event location
Brno
Event date
Jan 1, 2016
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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