Switching central trinucleotide sequences of DNA hepatmer regulates adsorption on mercury electrode

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F16%3A00090237" target="_blank" >RIV/00216224:14310/16:00090237 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1007/s00706-016-1689-7" target="_blank" >http://dx.doi.org/10.1007/s00706-016-1689-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00706-016-1689-7" target="_blank" >10.1007/s00706-016-1689-7</a>

Result language

angličtina

Original language name

Switching central trinucleotide sequences of DNA hepatmer regulates adsorption on mercury electrode

Original language description

The focus of the presented study is electrochemical investigation of DNA heptamers d(GCNNNGC) with a different center trinucleotide sequence (NNN = GAA, AAA, CCC and GGG, where A, C and G is adenine, cytosine and guanine, respectively). In phosphate-acetate buffer at pH 5.8 all heptamers were adsorbed on a hanging mercury electrode and further reduced and oxidized. The voltammetric reduction peaks of A and C moiety and oxidation peaks of G moiety at different concentrations (0.25 to 10 µmol•L-1) were analyzed. It was found that the changes in the central trinucleotide sequence of heptamers result in altered adsorption ability at a charged phase interface. An electron transfer process in an adsorptive state was evidenced by the elimination voltammetric procedure (EVP). For the evaluation of adsorption efficiency of heptamers the Langmuir adsorption model was applied and the adsorption coefficient b was calculated.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CF - Physical chemistry and theoretical chemistry

OECD FORD branch

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Project

<a href="/en/project/LH13053" target="_blank" >LH13053: Chemical and electrochemical analysis of purine derivatives and their copper complexes</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Monatshefte für Chemie - Chemical Monthly

ISSN

0026-9247

e-ISSN

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Volume of the periodical

147

Issue of the periodical within the volume

5

Country of publishing house

AT - AUSTRIA

Number of pages

8

Pages from-to

857-864

UT code for WoS article

000374172200003

EID of the result in the Scopus database

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