Anion-pi interactions in flavoproteins involve a substantial charge-transfer component

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F17%3A00094613" target="_blank" >RIV/00216224:14310/17:00094613 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/chem.201605307" target="_blank" >http://dx.doi.org/10.1002/chem.201605307</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/chem.201605307" target="_blank" >10.1002/chem.201605307</a>

Result language
angličtina
Original language name
Anion-pi interactions in flavoproteins involve a substantial charge-transfer component
Original language description
Anion-pi interactions have been shown to stabilize flavoproteins and to regulate the redox potential of the flavin cofactor. They are commonly attributed to electrostatic forces. Here we show that anion-flavin interactions have a substantial charge-transfer component. Our conclusion emanates from a multiapproach theoretical analysis and is backed by previously reported observations of absorption bands, originating from charge transfer between oxidized flavin and proximate cystein thiolate groups. This partial covalency of anion-flavin contacts renders classical simulations of flavoproteins questionable.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10403 - Physical chemistry

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)