First description of the emergence of Enterobacter asburiae producing IMI-2 carbapenemase in the Czech Republic
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F17%3A00108757" target="_blank" >RIV/00216224:14310/17:00108757 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/17:10365174 RIV/00064165:_____/17:10365174
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S221371651730187X?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S221371651730187X?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jgar.2017.10.001" target="_blank" >10.1016/j.jgar.2017.10.001</a>
Alternative languages
Result language
angličtina
Original language name
First description of the emergence of Enterobacter asburiae producing IMI-2 carbapenemase in the Czech Republic
Original language description
The acquired class A carbapenemase IMI-1 was originally described in an Enterobacter cloacae isolated in a Californian hospital in 1984 [1]. Since their first description, IMI-type carbapenemases have occasionally been detected in Enterobacteriaceae from the USA, Europe, the Far East and South Africa. Here we report the case of an IMI-2-producing Enterobacter asburiae identified in the Czech Republic. In 2016, E. asburiae Easb-36567cz was recovered from a patient admitted to a Czech hospital. Easb-36567cz was isolated from a rectal swab during routine screening for carbapenemase-producing Enterobacteriaceae (CPE). Easb-36567cz was resistant to aminopenicillins, aminopenicillin/sulbactam combinations, second-generation cephalosporins, aztreonam, carbapenems and colistin but was susceptible to piperacillin/tazobactam, cefotaxime, ceftazidime and various non-beta-lactam antibiotics (Table 1). Carbapenemase production was hypothesised by a positive result in the matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) imipenem hydrolysis assay [2]. Easb-36567cz tested negative by the ethylene diamine tetra-acetic acid (EDTA)–meropenem test, whilst the respective boronic acid–meropenem combined-disk test appeared positive indicating production of a class A carbapenemase. PCR and sequencing showed that Easb-36567cz carried blaIMI-2 [3].
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30100 - Basic medicine
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Global Antimicrobial Resistance
ISSN
2213-7165
e-ISSN
2213-7173
Volume of the periodical
11
Issue of the periodical within the volume
DEC
Country of publishing house
GB - UNITED KINGDOM
Number of pages
2
Pages from-to
98-99
UT code for WoS article
000416992000020
EID of the result in the Scopus database
2-s2.0-85032306295