All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Oil-based adjuvants delivered intradermally induce high primary IgG2 immune response in swine

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F17%3A00111749" target="_blank" >RIV/00216224:14310/17:00111749 - isvavai.cz</a>

  • Alternative codes found

    RIV/00027162:_____/17:N0000016

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S0034528817300474?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0034528817300474?via%3Dihub</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.rvsc.2017.03.007" target="_blank" >10.1016/j.rvsc.2017.03.007</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Oil-based adjuvants delivered intradermally induce high primary IgG2 immune response in swine

  • Original language description

    The effects of intradermal application of antigen with or without different adjuvants and activation of immune response are presented in this study. Six groups of six piglets each were immunized with keyhole limpet haemocyanin (KLH) antigen in combination with aluminium hydroxide or oil-based adjuvants (complete and incomplete Freund's adjuvants, Montanide ISA 206 and Emulsigen). IgG1 and IgG2 levels in sera were measured by KLH-specific ELISA. Interestingly, oil-based adjuvants induced high primary IgG2 response, suggesting the Thl lymphocyte polarization. Also, considering the similarities between human and porcine organism, we suggest that intradermal application could be considered as an effective vaccine delivery route in both veterinary and human medicine.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    40301 - Veterinary science

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    RESEARCH IN VETERINARY SCIENCE

  • ISSN

    0034-5288

  • e-ISSN

    1532-2661

  • Volume of the periodical

    114

  • Issue of the periodical within the volume

    OCT

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    3

  • Pages from-to

    41-43

  • UT code for WoS article

    000414881800008

  • EID of the result in the Scopus database

    2-s2.0-85015435515