Human White Adipose Tissue Metabolome: Current Perspective
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F18%3A00105235" target="_blank" >RIV/00216224:14310/18:00105235 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/18:73587953
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/full/10.1002/oby.22336" target="_blank" >https://onlinelibrary.wiley.com/doi/full/10.1002/oby.22336</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/oby.22336" target="_blank" >10.1002/oby.22336</a>
Alternative languages
Result language
angličtina
Original language name
Human White Adipose Tissue Metabolome: Current Perspective
Original language description
Objective Interest in metabolites produced by adipose tissue has increased substantially in the past several decades. Previously regarded as an inert energy storage depot, adipose tissue is now viewed as a complex metabolically active organ with considerable impact on human health. The emerging field of mass spectrometry-based metabolomics presents a powerful tool for the study of processes in complex biological matrices including adipose tissue. Results A large number of structurally distinct metabolites can be analyzed to facilitate the investigation of differences between physiological and pathophysiological metabolic profiles associated with adipose tissue. Understanding the molecular basis of adipose tissue regulation can thereby provide insight into the monitoring of obesity-related metabolic disorders and lead to the development of novel diagnostic and prognostic biomarkers. Conclusions This review provides the current state of knowledge, recent progress, and critical evaluation of metabolomics approaches in the context of white adipose tissue and obesity. An overview of basic principles and resources describing individual groups of metabolites analyzed in white adipose tissue and biological fluids is given. The focus is on metabolites that can serve as reliable biomarkers indicative of metabolic alterations associated with obesity.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30308 - Nutrition, Dietetics
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
OBESITY
ISSN
1930-7381
e-ISSN
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Volume of the periodical
26
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
1870-1878
UT code for WoS article
000450678700011
EID of the result in the Scopus database
2-s2.0-85055717972