Estimated dietary iodine intake as a predictor of placental size: evidence from the ELSPAC study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F18%3A00105834" target="_blank" >RIV/00216224:14310/18:00105834 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1186/s12986-018-0240-8" target="_blank" >http://dx.doi.org/10.1186/s12986-018-0240-8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s12986-018-0240-8" target="_blank" >10.1186/s12986-018-0240-8</a>

Result language

angličtina

Original language name

Estimated dietary iodine intake as a predictor of placental size: evidence from the ELSPAC study

Original language description

Background: The relationship between low iodine status and pregnancy-associated comorbidities has been known for decades. The relationship between iodine intake and placental pathologies is, however, far less clear. This study was designed to examine the relationship between dietary iodine intake and placental size while also focusing on typical adverse pregnancy outcomes. Method: The dietary iodine intake of 4711 pregnant women enrolled in the Czech part of the European Longitudinal Study of Pregnancy and Childhood (ELSPAC) in 1990-1991 was established using a 145-item food frequency questionnaire. Multivariate linear regression models were used to estimate the relationship between dietary iodine intake during pregnancy and placental weight. Additional models were constructed to investigate the relationship between estimated dietary iodine intake and adverse birth outcomes. Results: The estimated average iodine intake in the ELSPAC cohort was 106.6 mu g/day. In the fully adjusted model, estimated dietary iodine intake was found to be significantly negatively associated with placental weight (beta = -0.025, 95% CI: -0.044; -0.006, p = 0.011). Moreover, estimated dietary iodine intake was found to be significantly positively associated with the birth weight /placental weight ratio in the fully adjusted model (beta = -0.024, 95% CI: 0.004; 0.043, p = 0.016). Conclusions: This study provides evidence of a relationship between estimated dietary iodine intake and placental weight and the birth weight /placental weight ratio. Additional research is warranted to provide more insight into the role of iodine in early as well as late placentation.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30308 - Nutrition, Dietetics

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

NUTRITION & METABOLISM

ISSN

1743-7075

e-ISSN

—

Volume of the periodical

15

Issue of the periodical within the volume

JAN 17 2018

Country of publishing house

GB - UNITED KINGDOM

Number of pages

14

Pages from-to

1-14

UT code for WoS article

000422983500001

EID of the result in the Scopus database

2-s2.0-85040773411