Magnetic nanoparticles for smart electrochemical immunoassays: a review on recent developments
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F19%3A00109554" target="_blank" >RIV/00216224:14310/19:00109554 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s00604-019-3410-0" target="_blank" >http://dx.doi.org/10.1007/s00604-019-3410-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00604-019-3410-0" target="_blank" >10.1007/s00604-019-3410-0</a>
Alternative languages
Result language
angličtina
Original language name
Magnetic nanoparticles for smart electrochemical immunoassays: a review on recent developments
Original language description
This review (with 129 refs) summarizes the progress in electrochemical immunoassays combined with magnetic particles that was made in the past 5 years. The specifity of antibodies linked to electrochemical transduction (by amperometry, voltammetry, impedimetry or electrochemiluminescence) gains further attractive features by introducing magnetic nanoparticles (MNPs). This enables fairly easy preconcentration of analytes, minimizes matrix effects, and introduces an appropriate label. Following an introduction into the fundamentals of electrochemical immunoassays and on nanomaterials for respective uses, a large chapter addresses method for magnetic capture and preconcentration of analytes. A next chapter discusses commonly used labels such as dots, enzymes, metal and metal oxide nanoparticles and combined clusters. The large field of hybrid nanomaterials for use in such immunoassays is discussed next, with a focus on MNPs composites with various kinds of graphene variants, polydopamine, noble metal nanoparticles or nanotubes. Typical applications address clinical markers (mainly blood and urine parameters), diagnosis of cancer (markers and cells), detection of pathogens (with subsections on viruses and bacteria), and environmental and food contaminants as toxic agents and pesticides. A concluding section summarizes the present status, current challenges, and highlights future trends.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
<a href="/en/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Microchimica Acta
ISSN
0026-3672
e-ISSN
1436-5073
Volume of the periodical
186
Issue of the periodical within the volume
5
Country of publishing house
AT - AUSTRIA
Number of pages
26
Pages from-to
1-26
UT code for WoS article
000466376600005
EID of the result in the Scopus database
2-s2.0-85065026409