Are we approaching a post-monolithic era?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F20%3A00114433" target="_blank" >RIV/00216224:14310/20:00114433 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1002/jssc.201901331" target="_blank" >https://doi.org/10.1002/jssc.201901331</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/jssc.201901331" target="_blank" >10.1002/jssc.201901331</a>
Alternative languages
Result language
angličtina
Original language name
Are we approaching a post-monolithic era?
Original language description
Thirty years after their introduction, monolithic stationary phases are an important member of chromatographic phases. When compared to conventional particulate materials, the continuous internal structure of both inorganic silica and organic polymer monoliths allows some hydrodynamic and analytical possibilities that are not provided by conventional particulate stationary phases. Polymer-based monolithic stationary phases offer simple preparation and straightforward surface modification, which makes them very versatile materials that are applicable, for example, as chromatographic stationary phases, sample enrichment units, enzymatic reactors, and external trigger-responding materials. On the other hand, current polymer monoliths cannot compete with efficiency provided by superficially porous and sub 2 mu m particles. In this highlight article, I take advantage of the 30th anniversary of their introduction to discuss several concerns related to polymer-based monolithic stationary phases. Particularly, I focus on preparation repeatability, porous properties, swelling of the polymers in organic solvents, column efficiency for small molecules, and heterogeneity of dominant flow-through pores. In the end, I offer three possible approaches on how to overcome drawbacks related to stationary phases heterogeneity to further increase the applicability of polymer-based monolithic stationary phases.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
<a href="/en/project/GA17-11252S" target="_blank" >GA17-11252S: Tailoring selectivity of polymer-based monolithic stationary phases</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of separation science
ISSN
1615-9306
e-ISSN
1615-9314
Volume of the periodical
43
Issue of the periodical within the volume
9-10
Country of publishing house
DE - GERMANY
Number of pages
6
Pages from-to
1628-1633
UT code for WoS article
000512026000001
EID of the result in the Scopus database
2-s2.0-85079479713