Isoflavones
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F23%3A00130404" target="_blank" >RIV/00216224:14310/23:00130404 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/referenceworkentry/10.1007/978-3-030-81404-5_8-1" target="_blank" >https://link.springer.com/referenceworkentry/10.1007/978-3-030-81404-5_8-1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-030-81404-5_8-1" target="_blank" >10.1007/978-3-030-81404-5_8-1</a>
Alternative languages
Result language
angličtina
Original language name
Isoflavones
Original language description
Isoflavones, phenolic compounds with a 3-phenylchromen-4-one backbone, are plant-derived metabolites found primarily in the Fabaceae family. Hundreds of isoflavone structures have been identified so far. Regarding human nutrition, the most important of these are soybean isoflavones including daidzein, genistein, and glycitein. After ingestion, isoflavones are deglycosylated, demethylated, oxidized (or reduced), glucuronidated, or sulfated by enterocytes, liver cells, and intestinal microorganisms. Among the metabolites, daidzein metabolite equol has the greatest impact on human health. Due to their similarity to estrogens, equol and genistein, and to a lesser extent other isoflavones, exert estrogenic or antiestrogenic effects in mammals, leading to antimenopausal, cardioprotective, antiosteoporotic, and in the case of estrogen-related cancers, anticarcinogenic effects. Apart from these hormone-related activities, isoflavones possess antioxidant properties and influence several other biological processes. However, the health effects of food-derived isoflavones are dependent on the food matrices and also on the ability of intestinal microflora to produce equol. For the individuals who cannot produce equol, the consumption of milk is an alternative, as significant amounts of this metabolite are excreted into milk in cows fed feedstuffs rich in isoflavones. Thus, targeted cattle nutrition could result in the production of milk that can be considered a functional food.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Handbook of Food Bioactive Ingredients : Properties and Applications
ISBN
9783030814045
Number of pages of the result
27
Pages from-to
1-27
Number of pages of the book
990
Publisher name
Springer
Place of publication
Cham
UT code for WoS chapter
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