Impact of Varroa mite infestation on honey bees: Insight from proteomics and metabolomics
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F24%3A00139785" target="_blank" >RIV/00216224:14310/24:00139785 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Impact of Varroa mite infestation on honey bees: Insight from proteomics and metabolomics
Original language description
Varroa mites pose a significant threat to honey bee populations worldwide, impacting colony health and productivity. Parasitism by the Varroa mite is often associated with deformed wing virus (DWV) co-infection. In this study, we investigated the effect of Varroa mite infestation on short-living summer honey bees through comprehensive proteomics and metabolomics analyses, accompanied with the DWV loads evaluation. Our findings reveal profound alterations in the proteome and metabolome profiles of Varroa parasitised honey bees, indicative of systemic physiological perturbations. Specifically, we observed dysregulation in proteins responsible for nutrition, longevity, and hygienic behaviour. In Varroa parasitised bees, we detected an upregulation in proteins associated with energy metabolism, stress response, and immune function, which is consistent with our metabolomic data. Additionally, our analysis demonstrated a significant increase in DWV loads in Varroa parasitised honey bees, confirming the role of Varroa mites as vectors for viral transmission within honey bee colonies. These findings shed light on the multifaceted impact of Varroa mite infestation on honey bee health during the summer period.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10616 - Entomology
Result continuities
Project
<a href="/en/project/QL24010241" target="_blank" >QL24010241: Strategy for mitigating the influence of the Varroa destructor mite and associated viruses on the health and vitality of bee colonies in the changing climatic conditions of the Czech Republic</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů