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On Approximative Reachability Analysis of Biochemical Dynamical Systems

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F12%3A00057894" target="_blank" >RIV/00216224:14330/12:00057894 - isvavai.cz</a>

  • Result on the web

    <a href="http://link.springer.com/chapter/10.1007%2F978-3-642-35524-0_4" target="_blank" >http://link.springer.com/chapter/10.1007%2F978-3-642-35524-0_4</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/978-3-642-35524-0_4" target="_blank" >10.1007/978-3-642-35524-0_4</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    On Approximative Reachability Analysis of Biochemical Dynamical Systems

  • Original language description

    This is an extended version of the workshop paper, in which a new computational technique called quantitative discrete approximation has been introduced. The technique provides finite discrete approximation of continuous dynamical systems which is suitable especially for a significant class of biochemical dynamical systems. With decreasing granularity the approximation of behaviour between a discrete state and its successor converges to the behaviour of the original continuous system in the respective part of the phase space. This paper provides a detailed description of the method and algorithms solving the reachability problem in biochemical dynamical systems. The method is supplemented with heuristics for reducing the cardinality of the reachable state space. The algorithms are evaluated on six models (with numbers of variables ranging from 2 to 12).

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    IN - Informatics

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP202%2F11%2F0312" target="_blank" >GAP202/11/0312: Software Components in Embedded Systems: Development and Verification</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Transactions on Computational Systems Biology XIV

  • ISBN

    9783642355233

  • ISSN

    0302-9743

  • e-ISSN

  • Number of pages

    25

  • Pages from-to

    77-101

  • Publisher name

    Springer

  • Place of publication

    Heidelberg

  • Event location

    Aachen

  • Event date

    Jan 1, 2012

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article