Influence of circadian clocks on optimal regime of central C-N metabolism of cyanobacteria
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F18%3A00104828" target="_blank" >RIV/00216224:14330/18:00104828 - isvavai.cz</a>
Alternative codes found
RIV/86652079:_____/19:00497586
Result on the web
<a href="https://doi.org/10.1016/B978-0-12-814667-5.00009-X" target="_blank" >https://doi.org/10.1016/B978-0-12-814667-5.00009-X</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/B978-0-12-814667-5.00009-X" target="_blank" >10.1016/B978-0-12-814667-5.00009-X</a>
Alternative languages
Result language
angličtina
Original language name
Influence of circadian clocks on optimal regime of central C-N metabolism of cyanobacteria
Original language description
Mechanistic aspects of cyanobacteria clock and metabolism have been analyzed in considerable detail during recent decades, but only limited knowledge is available about particular link(s) between the clock and controlled metabolic processes. We describe a case study where we couple a mechanistic model of a circadian oscillator with a model of central carbon-nitrogen metabolism and apply formal methods based on temporal logic and bifurcation analysis to examine response of the metabolic part of the combined model to the autonomous clock oscillations. The analysis identified a set of parametric groups that, when applied to the in silico system, lead either to an optimal configuration of metabolic pathways for most efficient rhythmic function of the metabolism or to (oscillatory) system death. Under controlled conditions in monitored environments, such as cultivation in photobioreactors, the knowledge can be used for optimal regulation of production capacity that would reflect dynamic constraints of real world systems.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
20900 - Industrial biotechnology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Cyanobacteria: From Basic Science to Applications
ISBN
9780128146675
Number of pages of the result
14
Pages from-to
193-206
Number of pages of the book
522
Publisher name
Academic Press
Place of publication
Neuveden
UT code for WoS chapter
000509547100010