Clinical correlations of miR-21 expression in colorectal cancer patients and effects of its inhibition on DLD1 colon cancer cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F12%3A00057342" target="_blank" >RIV/00216224:14740/12:00057342 - isvavai.cz</a>
Alternative codes found
RIV/00209805:_____/12:#0000363
Result on the web
<a href="http://link.springer.com/article/10.1007%2Fs00384-012-1461-3" target="_blank" >http://link.springer.com/article/10.1007%2Fs00384-012-1461-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00384-012-1461-3" target="_blank" >10.1007/s00384-012-1461-3</a>

Result language
angličtina
Original language name
Clinical correlations of miR-21 expression in colorectal cancer patients and effects of its inhibition on DLD1 colon cancer cells
Original language description
MicroRNA-21 (miR-21) is one of the miRNAs that are frequently and highly overexpressed in tumor tissue of colorectal cancer patients. We confirmed over-expression of miR-21 in colorectal cancer patients and its correlation with advanced disease and shorter overall survival. Our results suggest that it is increased migration activity of colon cancer cells over-expressing miR-21 that can be responsible for these effects.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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