Burkholderia cenocepacia lectin A binding to heptoses from the bacterial lipopolysaccharide

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F12%3A00057548" target="_blank" >RIV/00216224:14740/12:00057548 - isvavai.cz</a>

Result on the web

<a href="http://glycob.oxfordjournals.org/content/22/10/1387.abstract" target="_blank" >http://glycob.oxfordjournals.org/content/22/10/1387.abstract</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/glycob/cws105" target="_blank" >10.1093/glycob/cws105</a>

Result language

angličtina

Original language name

Burkholderia cenocepacia lectin A binding to heptoses from the bacterial lipopolysaccharide

Original language description

Bacteria from the Burkholderia cepacia complex (Bcc) cause highly contagious pneumonia among cystic fibrosis (CF) patients. Among them, Burkholderia cenocepacia is one of the most dangerous in the Bcc and is the most frequent cause of morbidity and mortality in CF patients. Indeed, it is responsible of ?cepacia syndrome?, a deadly exacerbation of infection, that is the main cause of poor outcomes in lung transplantation. Burkholderia cenocepacia produces several soluble lectins with specificity for fucosylated and mannosylated glycoconjugates. These lectins are present on the bacterial cell surface and it has been proposed that they bind to lipopolysaccharide epitopes. In this work, we report on the interaction of one B. cenocepacia lectin, BC2L-A, with heptose and other manno configured sugar residues.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Glycobiology

ISSN

0959-6658

e-ISSN

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Volume of the periodical

22

Issue of the periodical within the volume

10

Country of publishing house

GB - UNITED KINGDOM

Number of pages

12

Pages from-to

1387-1398

UT code for WoS article

000308011800011

EID of the result in the Scopus database

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