Speeding up MS imaging with fast mirror scanning
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F12%3A00057870" target="_blank" >RIV/00216224:14740/12:00057870 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Speeding up MS imaging with fast mirror scanning
Original language description
High resolution mass spectrometry imaging (MSI) analysis may involve mass spectra recording from 10 000 or more measurement points. Though a new generation of mass spectrometers with kHz lasers brought significant decrease of MSI time, one image acquisition can still consume many hours. In such a device utilizing high repetition laser the total imaging time is no longer limited only by the data acquisition but also by the speed of the target stage translation. With a proper design of ion source optics,speeding up of the MSI can be achieved by substitution of the stage translation with a fast scanning mirror redirecting the desorption laser beam in micrometer scale. A prototype with 2 kHz 355 nm Nd:YAG laser and the fast precision scanning mirror was used to record 10 000 pixel MS map with 100 acquisitions per pixel in 12,5 minutes, an order of magnitude faster compared to the commercial instrument, 1 kHz AutoFlexTM Speed (Bruker Daltonics).
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů