Impairment of Brain Vessels May Contribute to Mortality in Patients With Parkinson's Disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F12%3A00064335" target="_blank" >RIV/00216224:14740/12:00064335 - isvavai.cz</a>
Alternative codes found
RIV/00159816:_____/12:#0000904
Result on the web
<a href="http://www.ncbi.nlm.nih.gov/pubmed/22692677" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/22692677</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/mds.25066" target="_blank" >10.1002/mds.25066</a>
Alternative languages
Result language
angličtina
Original language name
Impairment of Brain Vessels May Contribute to Mortality in Patients With Parkinson's Disease
Original language description
Background: The effect of brain-vessel pathology on mortality in 57 consecutive PD patients was studied. Methods: Baseline clinical, neuropsychological, ultrasonographic (US), and MR data obtained from patients who died (n = 18) during a 4-year follow-upperiod were compared with the data of patients who survived. Results: US/MRI data displayed a more-severe vascular impairment in deceased patients. Differences were significant between both groups with respect to age, clinical and cognitive status, intima-media thickness, and resistance index (indicators of large and small vessel impairment). The sum score of white-matter hyperintensities was significantly higher among decedents. A cluster analysis displayed two clusters that differed in the two parameters (i.e. in age and in sum score). Conclusions: This study provides evidence that comorbid atherosclerosis and otherwise subclinical impairment of brain vessels may contribute to mortality in PD.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Movement Disorders
ISSN
0885-3185
e-ISSN
—
Volume of the periodical
27
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
1168-1172
UT code for WoS article
000307387400030
EID of the result in the Scopus database
—