Chicken innate immune response to oral infection with Salmonella enterica serovar Enteritidis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F13%3A00066269" target="_blank" >RIV/00216224:14740/13:00066269 - isvavai.cz</a>
Alternative codes found
RIV/00027162:_____/13:#0000990
Result on the web
<a href="http://www.veterinaryresearch.org/content/44/1/37" target="_blank" >http://www.veterinaryresearch.org/content/44/1/37</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/1297-9716-44-37" target="_blank" >10.1186/1297-9716-44-37</a>
Alternative languages
Result language
angličtina
Original language name
Chicken innate immune response to oral infection with Salmonella enterica serovar Enteritidis
Original language description
The characterization of the immune response of chickens to Salmonella infection is usually limited to the quantification of expression of genes coding for cytokines, chemokines or antimicrobial peptides. However, processes occurring in the cecum of infected chickens are likely to be much more diverse. In this study we have therefore characterized the transcriptome and proteome in the chicken cecum after infection with Salmonella Enteritidis. Using a combination of 454 pyrosequencing, protein mass spectrometry and quantitative real-time PCR, we identified 48 down-and 56 up-regulated chicken genes after Salmonella Enteritidis infection. The most inducible gene was that coding for MMP7, exhibiting a 5952 fold induction 9 days post-infection. An inductionof greater than 100 fold was observed for IgG, IRG1, SAA, ExFABP, IL-22, TRAP6, MRP126, IFN gamma, iNOS, ES1, IL-1 beta, LYG2, IFIT5, IL-17, AVD, AH221 and SERPIN B.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
VETERINARY RESEARCH
ISSN
0928-4249
e-ISSN
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Volume of the periodical
44
Issue of the periodical within the volume
May
Country of publishing house
GB - UNITED KINGDOM
Number of pages
11
Pages from-to
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UT code for WoS article
000319449200001
EID of the result in the Scopus database
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