Structure-function relationships during transgenic telomerase expression in Arabidopsis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F13%3A00070046" target="_blank" >RIV/00216224:14740/13:00070046 - isvavai.cz</a>
Alternative codes found
RIV/68081707:_____/13:00399499
Result on the web
<a href="http://www.ncbi.nlm.nih.gov/pubmed/23278240" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/23278240</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/ppl.12021" target="_blank" >10.1111/ppl.12021</a>
Alternative languages
Result language
angličtina
Original language name
Structure-function relationships during transgenic telomerase expression in Arabidopsis
Original language description
Although telomerase (EC 2.7.7.49) is important for genome stability and totipotency of plant cells, the principles of its regulation are not well understood. Therefore, we studied subcellular localization and function of the full-length and truncated variants of the catalytic subunit of Arabidopsis thaliana telomerase, AtTERT, in planta. Our results show that multiple sites in AtTERT may serve as nuclear localization signals, as all the studied individual domains of the AtTERT were targeted to the nucleus and/or the nucleolus. Although the introduced genomic or cDNAAtTERT transgenes display expression at transcript and protein levels, they are not able to fully complement the lack of telomerase functions in tert -/- mutants. The failure to reconstitutetelomerase function in planta suggests a more complex telomerase regulation in plant cells than would be expected based on results of similar experiments in mammalian model systems.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PHYSIOLOGIA PLANTARUM
ISSN
0031-9317
e-ISSN
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Volume of the periodical
149
Issue of the periodical within the volume
1
Country of publishing house
DK - DENMARK
Number of pages
13
Pages from-to
114-126
UT code for WoS article
000323157900010
EID of the result in the Scopus database
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